Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II
Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Therapeutic use of cyclooxygenase-inhibiting (COX-inhibiting) nonsteroidal antiinflammatory drugs (NSAIDs) is often complicated by renal side effects including hypertension and edema. The present studies were undertaken to elucidate the roles of COX1 and COX2 in regulating blood pressure and renal function. COX2 inhibitors or gene knockout dramatic...
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Full title
Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II
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TN_cdi_proquest_journals_200550496
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_200550496
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ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/jci0214752