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Prostaglandin E^sub 2^ reduces radiation-induced epithelial apoptosis through a mechanism involving...

Prostaglandin E^sub 2^ reduces radiation-induced epithelial apoptosis through a mechanism involving...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_200554642

Prostaglandin E^sub 2^ reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation

About this item

Full title

Prostaglandin E^sub 2^ reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation

Publisher

Ann Arbor: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2004-12, Vol.114 (11), p.1676

Language

English

Formats

Publication information

Publisher

Ann Arbor: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Prostaglandin E2 (PGE2) synthesis modulates the response to radiation injury in the mouse intestinal epithelium through effects on crypt survival and apoptosis; however, the downstream signaling events have not been elucidated. WT mice receiving 16,16-dimethyl PGE2 (dmPGE2) had fewer apoptotic cells per crypt than untreated mice. Apoptosis in Bax(-...

Alternative Titles

Full title

Prostaglandin E^sub 2^ reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_200554642

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_200554642

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

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