PD-L1 negatively regulates CD4^sup +^CD25^sup +^Foxp3^sup +^ Tregs by limiting STAT-5 phosphorylatio...
PD-L1 negatively regulates CD4^sup +^CD25^sup +^Foxp3^sup +^ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV
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Publisher
Ann Arbor: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
Ann Arbor: American Society for Clinical Investigation
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Contents
CD4+CD25+Foxp3+ Tregs suppress autoimmune responses. In addition, they limit T cell responses during chronic infection, thereby minimizing T cell-dependent immunopathology. We sought to investigate how Tregs are regulated in the livers of patients chronically infected with HCV, where they control the balance between an adequate protective immune re...
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Full title
PD-L1 negatively regulates CD4^sup +^CD25^sup +^Foxp3^sup +^ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV
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TN_cdi_proquest_journals_200573477
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_200573477
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
