Prostaglandin D2 amplifies lupus disease through basophil accumulation in lymphoid organs
Prostaglandin D2 amplifies lupus disease through basophil accumulation in lymphoid organs
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Author / Creator
Pellefigues, Christophe , Dema, Barbara , Lamri, Yasmine , Saidoune, Fanny , Chavarot, Nathalie , Lohéac, Charlotte , Pacreau, Emeline , Dussiot, Michael , Bidault, Caroline , Marquet, Florian , Jablonski, Mathieu , Chemouny, Jonathan M. , Jouan, Fanny , Dossier, Antoine , Chauveheid, Marie-Paule , Gobert, Delphine , Papo, Thomas , Karasuyama, Hajime , Sacré, Karim , Daugas, Eric and Charles, Nicolas
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
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Scope and Contents
Contents
In systemic lupus erythematosus (SLE), autoantibody production can lead to kidney damage and failure, known as lupus nephritis. Basophils amplify the synthesis of autoantibodies by accumulating in secondary lymphoid organs. Here, we show a role for prostaglandin D
2
(PGD
2
) in the pathophysiology of SLE. Patients with SLE have increase...
Alternative Titles
Full title
Prostaglandin D2 amplifies lupus disease through basophil accumulation in lymphoid organs
Authors, Artists and Contributors
Author / Creator
Dema, Barbara
Lamri, Yasmine
Saidoune, Fanny
Chavarot, Nathalie
Lohéac, Charlotte
Pacreau, Emeline
Dussiot, Michael
Bidault, Caroline
Marquet, Florian
Jablonski, Mathieu
Chemouny, Jonathan M.
Jouan, Fanny
Dossier, Antoine
Chauveheid, Marie-Paule
Gobert, Delphine
Papo, Thomas
Karasuyama, Hajime
Sacré, Karim
Daugas, Eric
Charles, Nicolas
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2006814011
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2006814011
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03129-8
