Promoter methylation and inactivation of tumour-suppressor genes in oral squamous-cell carcinoma
Promoter methylation and inactivation of tumour-suppressor genes in oral squamous-cell carcinoma
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Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
Genetic alterations that lead to loss or changes in tumour-suppressor genes are known to contribute to oral carcinogenesis. Traditional molecular methods to detect such losses have relied on mutation analysis or deletion of the gene. However, epigenetic mechanisms could also contribute to silencing of tumour-suppressor genes. Methylation regions ri...
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Full title
Promoter methylation and inactivation of tumour-suppressor genes in oral squamous-cell carcinoma
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TN_cdi_proquest_journals_200924267
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_200924267
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ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(05)70540-4
