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Tumor Suppressor Function of the Interferon-Induced Double-Stranded RNA-Activated Protein Kinase

Tumor Suppressor Function of the Interferon-Induced Double-Stranded RNA-Activated Protein Kinase

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201255779

Tumor Suppressor Function of the Interferon-Induced Double-Stranded RNA-Activated Protein Kinase

About this item

Full title

Tumor Suppressor Function of the Interferon-Induced Double-Stranded RNA-Activated Protein Kinase

Publisher

Washington, DC: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1993-01, Vol.90 (1), p.232-236

Language

English

Formats

Publication information

Publisher

Washington, DC: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

RNA-dependent protein kinase is a Mr68,000 protein in human cells (p68 kinase) or a Mr65,000 protein in murine cells (p65 kinase). p65/p68 is a serine/threonine kinase induced by interferon treatment and generally activated by double-stranded RNAs. Once activated, the known function of this kinase is inhibition of protein synthesis through phosphor...

Alternative Titles

Full title

Tumor Suppressor Function of the Interferon-Induced Double-Stranded RNA-Activated Protein Kinase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201255779

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201255779

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.90.1.232

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