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Expression and Functional Significance of an Additional Ligand For CTLA-4

Expression and Functional Significance of an Additional Ligand For CTLA-4

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201265641

Expression and Functional Significance of an Additional Ligand For CTLA-4

About this item

Full title

Expression and Functional Significance of an Additional Ligand For CTLA-4

Publisher

Washington, DC: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1993-12, Vol.90 (23), p.11054-11058

Language

English

Formats

Publication information

Publisher

Washington, DC: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

Effective T-cell activation requires antigen/major histocompatibility complex engagement by the T-cell receptor complex in concert with one or more costimulatory molecules. Recent studies have suggested that the B7 molecule, expressed on most antigen presenting cells, functions as a costimulatory molecule through its interaction with CD28 on T cell...

Alternative Titles

Full title

Expression and Functional Significance of an Additional Ligand For CTLA-4

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201265641

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201265641

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.90.23.11054

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