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A Single Active Site Residue Directs Oxygenation Stereospecificity in Lipoxygenases: Stereocontrol I...

A Single Active Site Residue Directs Oxygenation Stereospecificity in Lipoxygenases: Stereocontrol I...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201286592

A Single Active Site Residue Directs Oxygenation Stereospecificity in Lipoxygenases: Stereocontrol Is Linked to the Position of Oxygenation

About this item

Full title

A Single Active Site Residue Directs Oxygenation Stereospecificity in Lipoxygenases: Stereocontrol Is Linked to the Position of Oxygenation

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2004-11, Vol.101 (44), p.15579-15584

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Lipoxygenases are a class of dioxygenases that form hydroperoxy fatty acids with distinct positional and stereo configurations. Several amino acid residues influencing regiospecificity have been identified, whereas the basis of stereocontrol is not understood. We have now identified a single residue in the lipoxygenase catalytic domain that is impo...

Alternative Titles

Full title

A Single Active Site Residue Directs Oxygenation Stereospecificity in Lipoxygenases: Stereocontrol Is Linked to the Position of Oxygenation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201286592

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201286592

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0406727101

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