A Single Active Site Residue Directs Oxygenation Stereospecificity in Lipoxygenases: Stereocontrol I...
A Single Active Site Residue Directs Oxygenation Stereospecificity in Lipoxygenases: Stereocontrol Is Linked to the Position of Oxygenation
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Lipoxygenases are a class of dioxygenases that form hydroperoxy fatty acids with distinct positional and stereo configurations. Several amino acid residues influencing regiospecificity have been identified, whereas the basis of stereocontrol is not understood. We have now identified a single residue in the lipoxygenase catalytic domain that is impo...
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A Single Active Site Residue Directs Oxygenation Stereospecificity in Lipoxygenases: Stereocontrol Is Linked to the Position of Oxygenation
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TN_cdi_proquest_journals_201286592
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201286592
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0406727101