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The Cannabinoid WIN 55,212-2 Inhibits Transient Receptor Potential Vanilloid 1 (TRPV1) and Evokes Pe...

The Cannabinoid WIN 55,212-2 Inhibits Transient Receptor Potential Vanilloid 1 (TRPV1) and Evokes Pe...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201302668

The Cannabinoid WIN 55,212-2 Inhibits Transient Receptor Potential Vanilloid 1 (TRPV1) and Evokes Peripheral Antihyperalgesia via Calcineurin

About this item

Full title

The Cannabinoid WIN 55,212-2 Inhibits Transient Receptor Potential Vanilloid 1 (TRPV1) and Evokes Peripheral Antihyperalgesia via Calcineurin

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2006-07, Vol.103 (30), p.11393-11398

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Cannabinoids can evoke antihyperalgesia and antinociception at a peripheral site of action. However, the signaling pathways mediating these effects are not clearly understood. We tested the hypothesis that certain cannabinoids directly inhibit peripheral capsaicin-sensitive nociceptive neurons by dephosphorylating and desensitizing transient recept...

Alternative Titles

Full title

The Cannabinoid WIN 55,212-2 Inhibits Transient Receptor Potential Vanilloid 1 (TRPV1) and Evokes Peripheral Antihyperalgesia via Calcineurin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201302668

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201302668

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0603861103

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