Functional characterization of human variants of the mu-opioid receptor gene
Functional characterization of human variants of the mu-opioid receptor gene
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Opioids and their receptors have an important role in analgesia and alcohol and substance use disorders (ASUD). We have identified several naturally occurring amino acid changing variants of the human mu-opioid receptor (MOR), and assessed the functional consequences of these previously undescribed variants in stably expressing cell lines. Several...
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Functional characterization of human variants of the mu-opioid receptor gene
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TN_cdi_proquest_journals_201310695
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201310695
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0904509106