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Impaired glutathione synthesis in schizophrenia: Convergent genetic and functional evidence

Impaired glutathione synthesis in schizophrenia: Convergent genetic and functional evidence

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201320692

Impaired glutathione synthesis in schizophrenia: Convergent genetic and functional evidence

About this item

Full title

Impaired glutathione synthesis in schizophrenia: Convergent genetic and functional evidence

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (42), p.16621-16626

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Schizophrenia is a complex multifactorial brain disorder with a genetic component. Convergent evidence has implicated oxidative stress and glutathione (GSH) deficits in the pathogenesis of this disease. The aim of the present study was to test whether schizophrenia is associated with a deficit of GSH synthesis. Cultured skin fibroblasts from schizo...

Alternative Titles

Full title

Impaired glutathione synthesis in schizophrenia: Convergent genetic and functional evidence

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201320692

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201320692

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0706778104

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