Osteoblast expression of an engineered G^sub s^-coupled receptor dramatically increases bone mass
Osteoblast expression of an engineered G^sub s^-coupled receptor dramatically increases bone mass
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Publisher
Washington: National Academy of Sciences
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Language
English
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Publisher
Washington: National Academy of Sciences
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Contents
Osteoblasts are essential for maintaining bone mass, avoiding osteoporosis, and repairing injured bone. Activation of osteoblast G protein-coupled receptors (GPCRs), such as the parathyroid hormone receptor, can increase bone mass; however, the anabolic mechanisms are poorly understood. Here we use "Rs1," an engineered GPCR with constitutive G... s...
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Full title
Osteoblast expression of an engineered G^sub s^-coupled receptor dramatically increases bone mass
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TN_cdi_proquest_journals_201334666
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201334666
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ISSN
0027-8424
E-ISSN
1091-6490
