Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease
Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Our previous analyses showed that allopregnanolone (APα) significantly increased proliferation of rodent and human neural progenitor cells in vitro. In this study, we investigated the efficacy of APα to promote neurogenesis in the hippocampal subgranular zone (SGZ), to reverse learning and memory deficits in 3-month-old male triple transgenic mouse...
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Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease
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TN_cdi_proquest_journals_201335755
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201335755
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1001422107
