Antibody-Enhanced Pneumococcal Adherence Requires IgA1 Protease
Antibody-Enhanced Pneumococcal Adherence Requires IgA1 Protease
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
IgA, the major class of Ig in secretions, classically functions by interfering with microbial attachment to host tissues. Many mucosal pathogens, including Streptococcus pneumoniae, express an IgA1 protease that may circumvent the protective effects of this Ig subclass. Because these proteases are specific for human IgA1, we generated human mAbs to...
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Full title
Antibody-Enhanced Pneumococcal Adherence Requires IgA1 Protease
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TN_cdi_proquest_journals_201337501
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201337501
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0637469100
