Mice Lacking Dipeptidyl Peptidase IV Are Protected against Obesity and Insulin Resistance
Mice Lacking Dipeptidyl Peptidase IV Are Protected against Obesity and Insulin Resistance
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Dipeptidyl peptidase IV (DP-IV), a member of the prolyl oligopeptidase family of peptidases, is involved in the metabolic inactivation of a glucose-dependent insulinotropic hormone, glucagon-like peptide 1 (GLP-1), and other incretin hormones. Here, we investigated the impact of DP-IV deficiency on body weight control and insulin sensitivity in mic...
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Mice Lacking Dipeptidyl Peptidase IV Are Protected against Obesity and Insulin Resistance
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TN_cdi_proquest_journals_201341506
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201341506
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0631828100