The Unique Insert in Myosin VI Is a Structural Calcium-Calmodulin Binding Site
The Unique Insert in Myosin VI Is a Structural Calcium-Calmodulin Binding Site
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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Myosin VI contains an inserted sequence that is unique among myosin superfamily members and has been suggested to be a determinant of the reverse directionality and unusual motility of the motor. It is thought that each head of a two-headed myosin VI molecule binds one calmodulin (CaM) by means of a single "IQ motif". Using truncations of the myosi...
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The Unique Insert in Myosin VI Is a Structural Calcium-Calmodulin Binding Site
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TN_cdi_proquest_journals_201356298
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201356298
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0306892101