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A Chemical Inhibitor of N-WASP Reveals a New Mechanism for Targeting Protein Interactions

A Chemical Inhibitor of N-WASP Reveals a New Mechanism for Targeting Protein Interactions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201367187

A Chemical Inhibitor of N-WASP Reveals a New Mechanism for Targeting Protein Interactions

About this item

Full title

A Chemical Inhibitor of N-WASP Reveals a New Mechanism for Targeting Protein Interactions

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2001-09, Vol.98 (19), p.10624-10629

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Cell morphology and motility are governed largely by complex signaling networks that ultimately engage the actin cytoskeleton. Understanding how individual circuits contribute to the process of forming cellular structures would be aided greatly by the availability of specific chemical inhibitors. We have used a novel chemical screen in Xenopus cell...

Alternative Titles

Full title

A Chemical Inhibitor of N-WASP Reveals a New Mechanism for Targeting Protein Interactions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201367187

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201367187

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.201393198

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