Induction of a Proinflammatory Program in Normal Human Thyrocytes by the RET/PTC1 Oncogene
Induction of a Proinflammatory Program in Normal Human Thyrocytes by the RET/PTC1 Oncogene
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Author / Creator
Maria Grazia Borrello , Luisella Alberti , Andrew Fischer , Debora Degl'Innocenti , Cristina Ferrario , Gariboldi, Manuela , Federica Marchesi , Paola Allavena , Greco, Angela , Paola Collini , Silvana Pilotti , Giuliana Cassinelli , Paola Bressan , Laura Fugazzola , Mantovani, Alberto and Pierotti, Marco A.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Rearrangements of the RET receptor tyrosine kinase gene generating RET/PTC oncogenes are specific to papillary thyroid carcinoma (PTC), the most frequent thyroid tumor. Here, we show that the RET/PTC1 oncogene, when exogenously expressed in primary normal human thyrocytes, induces the expression of a large set of genes involved in inflammation and...
Alternative Titles
Full title
Induction of a Proinflammatory Program in Normal Human Thyrocytes by the RET/PTC1 Oncogene
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Record Identifier
TN_cdi_proquest_journals_201370023
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201370023
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0503039102
