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Long-term, progressive hippocampal cell loss and dysfunction induced by early-life administration of...

Long-term, progressive hippocampal cell loss and dysfunction induced by early-life administration of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201376705

Long-term, progressive hippocampal cell loss and dysfunction induced by early-life administration of corticotropin-releasing hormone reproduce the effects of early

About this item

Full title

Long-term, progressive hippocampal cell loss and dysfunction induced by early-life administration of corticotropin-releasing hormone reproduce the effects of early

Publisher

Washington: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2001-07, Vol.98 (15), p.8856

Language

English

Formats

Publication information

Publisher

Washington: National Academy of Sciences

More information

Scope and Contents

Contents

Stress early in postnatal life may result in long-term memory deficits and selective loss of hippocampal neurons. We report that administration of corticotropin-releasing hormone (CRH), the key limbic stress modulator, to the brains of immature rats reproduced the consequences of early-life stress, reducing memory functions throughout life.

Alternative Titles

Full title

Long-term, progressive hippocampal cell loss and dysfunction induced by early-life administration of corticotropin-releasing hormone reproduce the effects of early

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201376705

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201376705

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

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