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Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic...

Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201386477

Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic cell activation

About this item

Full title

Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic cell activation

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2007-09, Vol.104 (38), p.15087-15092

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Increased production of tumor necrosis factor α (TNF) in the bone marrow (BM) in response to both oxidative stress and T cell activation contributes to the bone loss induced by estrogen deficiency, but it is presently unknown whether oxidative stress causes bone loss through T cells. Here we show that ovariectomy causes an accumulation in the BM of...

Alternative Titles

Full title

Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic cell activation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201386477

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201386477

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0703610104

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