Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated...
Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by δ subunit-containing GABAA receptors
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United States: National Acad Sciences
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Language
English
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United States: National Acad Sciences
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Contents
Neuroactive steroids are potent modulators of γ-aminobutyric acid type A receptors (GABA A Rs), and their behavioral effects are generally viewed in terms of altered inhibitory synaptic transmission. Here we report that, at concentrations known to occur in vivo , neuroactive steroids specifically enhance a tonic inhibitory conductance in central ne...
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Full title
Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by δ subunit-containing GABAA receptors
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TN_cdi_proquest_journals_201399557
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201399557
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2435457100
