Log in to save to my catalogue

The role of platelet adhesion receptor GPIb[alpha] far exceeds that of its main ligand, von Willebra...

The role of platelet adhesion receptor GPIb[alpha] far exceeds that of its main ligand, von Willebra...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201405817

The role of platelet adhesion receptor GPIb[alpha] far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis

About this item

Full title

The role of platelet adhesion receptor GPIb[alpha] far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis

Publisher

Washington: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (45), p.16900

Language

English

Formats

Publication information

Publisher

Washington: National Academy of Sciences

More information

Scope and Contents

Contents

GPIbα binding to von Willebrand factor (VWF) exposed at a site of vascular injury is thought to be the first step in the formation of a hemostatic plug. However, our previous studies in VWF-deficient mice demonstrated delayed but not absent arterial thrombus formation, suggesting that, under these conditions, GPIbα may bind other ligands or that a...

Alternative Titles

Full title

The role of platelet adhesion receptor GPIb[alpha] far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201405817

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201405817

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

How to access this item