Human Langerhans cells induce distinct IL-22-producing CD4⁺ T cells lacking IL-17 production
Human Langerhans cells induce distinct IL-22-producing CD4⁺ T cells lacking IL-17 production
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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IL-22 is a cytokine that acts mainly on epithelial cells. In the skin, it mediates keratinocyte proliferation and epidermal hyperplasia and is thought to play a central role in inflammatory diseases with marked epidermal acanthosis, such as psoriasis. Although IL-22 was initially considered a Th17 cytokine, increasing evidence suggests that T helpe...
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Human Langerhans cells induce distinct IL-22-producing CD4⁺ T cells lacking IL-17 production
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TN_cdi_proquest_journals_201407632
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201407632
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.0911472106
