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Fibronectin forms the most extensible biological fibers displaying switchable force-exposed cryptic...

Fibronectin forms the most extensible biological fibers displaying switchable force-exposed cryptic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201407677

Fibronectin forms the most extensible biological fibers displaying switchable force-exposed cryptic binding sites

About this item

Full title

Fibronectin forms the most extensible biological fibers displaying switchable force-exposed cryptic binding sites

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-10, Vol.106 (43), p.18267-18272

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Rather than maximizing toughness, as needed for silk and muscle titin fibers to withstand external impact, the much softer extracellular matrix fibers made from fibronectin (Fn) can be stretched by cell generated forces and display extraordinary extensibility. We show that Fn fibers can be extended more than 8-fold (>700% strain) before 50% of the...

Alternative Titles

Full title

Fibronectin forms the most extensible biological fibers displaying switchable force-exposed cryptic binding sites

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201407677

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201407677

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0907518106

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