LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosph...
LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of [beta]-catenin
About this item
Full title
Author / Creator
Publisher
Washington: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
Washington: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Wnt/β-catenin signaling controls various cell fates in metazoan development and is misregulated in several cancers and developmental disorders. Binding of a Wnt ligand to its transmembrane coreceptors inhibits phosphorylation and degradation of the transcriptional coactivator β-catenin, which then translocates to the nucleus to regulate target gene...
Alternative Titles
Full title
LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of [beta]-catenin
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_201409260
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201409260
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
