Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties
Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties
About this item
Full title
Author / Creator
Wang, Jun , Kodali, Srinivas , Lee, Sang Ho , Galgoci, Andrew , Painter, Ronald , Dorso, Karen , Racine, Fred , Motyl, Mary , Hernandez, Lorraine , Tinney, Elizabeth , Colletti, Steven L , Herath, Kithsiri , Cummings, Richard , Salazar, Oscar , González, Ignacio , Basilio, Angela , Vicente, Francisca , Genilloud, Olga , Pelaez, Fernando , Jayasuriya, Hiranthi , Young, Katherine , Cully, Doris F and Singh, Sheo B
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Emergence of bacterial resistance is a major issue for all classes of antibiotics; therefore, the identification of new classes is critically needed. Recently we reported the discovery of platensimycin by screening natural product extracts using a target-based whole-cell strategy with antisense silencing technology in concert with cell free biochem...
Alternative Titles
Full title
Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties
Authors, Artists and Contributors
Author / Creator
Kodali, Srinivas
Lee, Sang Ho
Galgoci, Andrew
Painter, Ronald
Dorso, Karen
Racine, Fred
Motyl, Mary
Hernandez, Lorraine
Tinney, Elizabeth
Colletti, Steven L
Herath, Kithsiri
Cummings, Richard
Salazar, Oscar
González, Ignacio
Basilio, Angela
Vicente, Francisca
Genilloud, Olga
Pelaez, Fernando
Jayasuriya, Hiranthi
Young, Katherine
Cully, Doris F
Singh, Sheo B
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_201413165
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201413165
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0700746104
