Log in to save to my catalogue

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201429655

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

About this item

Full title

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-04, Vol.107 (16), p.7455-7460

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Whereas cell cycle arrest, apoptosis, and senescence are traditionally thought of as the major functions of the tumor suppressor p53, recent studies revealed two unique functions for this protein: p53 regulates cellular energy metabolism and antioxidant defense mechanisms. Here, we identify glutaminase 2 (GLS2) as a previously uncharacterized p53 t...

Alternative Titles

Full title

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201429655

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201429655

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1001006107

How to access this item