Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Whereas cell cycle arrest, apoptosis, and senescence are traditionally thought of as the major functions of the tumor suppressor p53, recent studies revealed two unique functions for this protein: p53 regulates cellular energy metabolism and antioxidant defense mechanisms. Here, we identify glutaminase 2 (GLS2) as a previously uncharacterized p53 t...
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Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
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TN_cdi_proquest_journals_201429655
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201429655
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1001006107