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Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start poi...

Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start poi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201430188

Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke

About this item

Full title

Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-04, Vol.107 (15), p.6799-6804

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The powerstroke of the myosin motor is the basis of cell division and bodily movement, but has eluded empirical description due to the short lifetime and low abundance of intermediates during force generation. To gain insight into this process, we used well-established single-tryptophan and pyrene fluorescent sensors and electron microscopy to char...

Alternative Titles

Full title

Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201430188

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201430188

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0907585107

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