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Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription

Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201432831

Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription

About this item

Full title

Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2007-08, Vol.104 (34), p.13690-13695

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

We have identified a conserved region in the C-terminal domain of bromodomain-containing protein 4 (BRD4) that mediates its specific interaction with positive transcription elongation factor b (P-TEFb). This domain is highly conserved in testis-specific bromodomain protein (BRDT) and Drosophila fs(1)h. Both BRDT and fs(1)h specifically interact wit...

Alternative Titles

Full title

Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_201432831

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201432831

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0705053104

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