Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoiet...
Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Hematopoietic stem cells (HSCs) execute self-renewal divisions throughout fetal and adult life, although some of their properties do alter. Here we analyzed the magnitude and timing of changes in the self-renewal properties and differentiated cell outputs of transplanted HSCs obtained from different sources during development. We also assessed the...
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Full title
Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties
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TN_cdi_proquest_journals_201434954
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_201434954
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0700460104
