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Taurine protects dopaminergic neurons in a mouse Parkinson’s disease model through inhibition of mic...

Taurine protects dopaminergic neurons in a mouse Parkinson’s disease model through inhibition of mic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2019482445

Taurine protects dopaminergic neurons in a mouse Parkinson’s disease model through inhibition of microglial M1 polarization

About this item

Full title

Taurine protects dopaminergic neurons in a mouse Parkinson’s disease model through inhibition of microglial M1 polarization

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2018-03, Vol.9 (4), p.435-13, Article 435

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Microglia-mediated neuroinflammation is implicated in multiple neurodegenerative disorders, including Parkinson’s disease (PD). Hence, the modulatioein of sustained microglial activation may have therapeutic potential. This study is designed to test the neuroprotective efficacy of taurine, a major intracellular free β-amino acid in mammalian tissue...

Alternative Titles

Full title

Taurine protects dopaminergic neurons in a mouse Parkinson’s disease model through inhibition of microglial M1 polarization

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2019482445

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2019482445

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-018-0468-2

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