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Association between ALDH2 and ADH1B polymorphisms, alcohol drinking and gastric cancer: a replicatio...

Association between ALDH2 and ADH1B polymorphisms, alcohol drinking and gastric cancer: a replicatio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2021167632

Association between ALDH2 and ADH1B polymorphisms, alcohol drinking and gastric cancer: a replication and mediation analysis

About this item

Full title

Association between ALDH2 and ADH1B polymorphisms, alcohol drinking and gastric cancer: a replication and mediation analysis

Publisher

Tokyo: Springer Japan

Journal title

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2018-11, Vol.21 (6), p.936-945

Language

English

Formats

Publication information

Publisher

Tokyo: Springer Japan

More information

Scope and Contents

Contents

Background
Aldehyde dehydrogenase 2 (
ALDH2
; rs671, Glu504Lys) and alcohol dehydrogenase 1B (
ADH1B
; rs1229984, His47Arg) polymorphisms have a strong impact on carcinogenic acetaldehyde accumulation after alcohol drinking. To date, however, evidence for a significant
ALDH2
–alcohol drinking interaction and a mediation effect...

Alternative Titles

Full title

Association between ALDH2 and ADH1B polymorphisms, alcohol drinking and gastric cancer: a replication and mediation analysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2021167632

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2021167632

Other Identifiers

ISSN

1436-3291

E-ISSN

1436-3305

DOI

10.1007/s10120-018-0823-0

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