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Randomized phase 2 study of gemcitabine and cisplatin with or without vitamin supplementation in pat...

Randomized phase 2 study of gemcitabine and cisplatin with or without vitamin supplementation in pat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2030541494

Randomized phase 2 study of gemcitabine and cisplatin with or without vitamin supplementation in patients with advanced esophagogastric cancer

About this item

Full title

Randomized phase 2 study of gemcitabine and cisplatin with or without vitamin supplementation in patients with advanced esophagogastric cancer

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cancer chemotherapy and pharmacology, 2018-07, Vol.82 (1), p.39-48

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
Preclinical research and prior clinical observations demonstrated reduced toxicity and suggested enhanced efficacy of cisplatin due to folic acid and vitamin B12 suppletion. In this randomized phase 2 trial, we evaluated the addition of folic acid and vitamin B12 to first-line palliative cisplatin and gemcitabine in patients with advance...

Alternative Titles

Full title

Randomized phase 2 study of gemcitabine and cisplatin with or without vitamin supplementation in patients with advanced esophagogastric cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2030541494

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2030541494

Other Identifiers

ISSN

0344-5704

E-ISSN

1432-0843

DOI

10.1007/s00280-018-3588-6

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