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Effect of vedolizumab (anti-α4β7-integrin) therapy on histological healing and mucosal gene expressi...

Effect of vedolizumab (anti-α4β7-integrin) therapy on histological healing and mucosal gene expressi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2043343257

Effect of vedolizumab (anti-α4β7-integrin) therapy on histological healing and mucosal gene expression in patients with UC

About this item

Full title

Effect of vedolizumab (anti-α4β7-integrin) therapy on histological healing and mucosal gene expression in patients with UC

Publisher

England: BMJ Publishing Group LTD

Journal title

Gut, 2018-01, Vol.67 (1), p.43-52

Language

English

Formats

Publication information

Publisher

England: BMJ Publishing Group LTD

More information

Scope and Contents

Contents

ObjectiveLymphocyte recruitment to the inflamed gut is increased in UC. Inhibition of this cell trafficking by vedolizumab (VDZ) was successful in inducing and maintaining remission and in induction of endoscopic mucosal healing. There are no data on histological healing with VDZ. We studied histological changes following VDZ therapy and compared g...

Alternative Titles

Full title

Effect of vedolizumab (anti-α4β7-integrin) therapy on histological healing and mucosal gene expression in patients with UC

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2043343257

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2043343257

Other Identifiers

ISSN

0017-5749

E-ISSN

1468-3288

DOI

10.1136/gutjnl-2016-312293

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