Extracellular Matrix Cross-Linking Enhances Fibroblast Growth and Protects against Matrix Proteolysi...
Extracellular Matrix Cross-Linking Enhances Fibroblast Growth and Protects against Matrix Proteolysis in Lung Fibrosis
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Publisher
United States: American Thoracic Society
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Language
English
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Publisher
United States: American Thoracic Society
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Scope and Contents
Contents
Idiopathic pulmonary fibrosis (IPF) is characterized by accumulation of extracellular matrix (ECM) proteins and fibroblast proliferation. ECM cross-linking enzymes have been implicated in fibrotic diseases, and we hypothesized that the ECM in IPF is abnormally cross-linked, which enhances fibroblast growth and resistance to normal ECM turnover. We...
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Full title
Extracellular Matrix Cross-Linking Enhances Fibroblast Growth and Protects against Matrix Proteolysis in Lung Fibrosis
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Record Identifier
TN_cdi_proquest_journals_2043654468
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2043654468
Other Identifiers
ISSN
1044-1549
E-ISSN
1535-4989
DOI
10.1165/rcmb.2016-0379OC
