SCF[beta]-TRCP controls oncogenic transformation and neural differentiation through REST degradation
SCF[beta]-TRCP controls oncogenic transformation and neural differentiation through REST degradation
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London: Nature Publishing Group
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English
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London: Nature Publishing Group
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The RE1-silencing transcription factor (REST, also known as NRSF) is a master repressor of neuronal gene expression and neuronal programmes in non-neuronal lineages. Recently, REST was identified as a human tumour suppressor in epithelial tissues, suggesting that its regulation may have important physiological and pathological consequences. However...
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SCF[beta]-TRCP controls oncogenic transformation and neural differentiation through REST degradation
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TN_cdi_proquest_journals_204542091
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_204542091
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature06780
