KMT2D/MLL2 inactivation is associated with recurrence in adult-type granulosa cell tumors of the ova...
KMT2D/MLL2 inactivation is associated with recurrence in adult-type granulosa cell tumors of the ovary
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Adult-type granulosa cell tumors of the ovary (aGCTs) are rare gynecologic malignancies that exhibit a high frequency of somatic
FOXL2
c.C402G (p.Cys134Trp) mutation. Treatment of relapsed aGCT remains a significant clinical challenge. Here we show, using whole-exome and cancer gene panel sequencing of 79 aGCTs from two independent cohorts, t...
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Full title
KMT2D/MLL2 inactivation is associated with recurrence in adult-type granulosa cell tumors of the ovary
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TN_cdi_proquest_journals_2060856176
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2060856176
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-04950-x
