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The Histone H3-H4 Tetramer is a Copper Reductase Enzyme

The Histone H3-H4 Tetramer is a Copper Reductase Enzyme

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068559453

The Histone H3-H4 Tetramer is a Copper Reductase Enzyme

About this item

Full title

The Histone H3-H4 Tetramer is a Copper Reductase Enzyme

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-07

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Ancestral histones were present in organisms with small genomes, no nucleus, and little evidence for epigenetic regulation, suggesting histones may have additional older functions. We report that the histone H3-H4 tetramer is an enzyme that catalyzes the reduction of Cu2+ to Cu1+ when assembled in vitro from recombinant histones. Mutations of resid...

Alternative Titles

Full title

The Histone H3-H4 Tetramer is a Copper Reductase Enzyme

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2068559453

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068559453

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/350652