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Co-expression of MDM2 and CDK4 in transformed human mesenchymal stem cells induces dedifferentiated...

Co-expression of MDM2 and CDK4 in transformed human mesenchymal stem cells induces dedifferentiated...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068824849

Co-expression of MDM2 and CDK4 in transformed human mesenchymal stem cells induces dedifferentiated liposarcoma potency

About this item

Full title

Co-expression of MDM2 and CDK4 in transformed human mesenchymal stem cells induces dedifferentiated liposarcoma potency

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2018-04

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Amplification and overexpression of MDM2 and CDK4 are well-known diagnostic criteria of well-differentiated liposarcoma (WDLPS)/dedifferentiated liposarcoma (DDLPS). Although it was reported that depletion of MDM2 or CDK4 decreased proliferation in DDLPS cell lines, it remains unclear whether MDM2 and CDK4 induce WDLPS/DDLPS tumorigenesis. We exami...

Alternative Titles

Full title

Co-expression of MDM2 and CDK4 in transformed human mesenchymal stem cells induces dedifferentiated liposarcoma potency

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2068824849

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068824849

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/293068