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Pharmacological modulation of AMPA receptor surface diffusion restores hippocampal synaptic plastici...

Pharmacological modulation of AMPA receptor surface diffusion restores hippocampal synaptic plastici...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068831854

Pharmacological modulation of AMPA receptor surface diffusion restores hippocampal synaptic plasticity and memory in Huntington's disease

About this item

Full title

Pharmacological modulation of AMPA receptor surface diffusion restores hippocampal synaptic plasticity and memory in Huntington's disease

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2018-04

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Impaired hippocampal synaptic plasticity is increasingly considered to play an important role in cognitive impairment in Huntington disease (HD). However, the molecular basis of synaptic plasticity defects is not fully understood. Combining live-cell nanoparticle tracking and super-resolution imaging, we show that dysregulation of AMPA receptors (A...

Alternative Titles

Full title

Pharmacological modulation of AMPA receptor surface diffusion restores hippocampal synaptic plasticity and memory in Huntington's disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2068831854

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068831854

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/297069