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A systematic survey of human tissue-specific gene expression and splicing reveals new opportunities...

A systematic survey of human tissue-specific gene expression and splicing reveals new opportunities...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068831941

A systematic survey of human tissue-specific gene expression and splicing reveals new opportunities for therapeutic target identification and evaluation

About this item

Full title

A systematic survey of human tissue-specific gene expression and splicing reveals new opportunities for therapeutic target identification and evaluation

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2018-04

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Differences in the expression of genes and their splice isoforms across human tissues are fundamental factors to consider for therapeutic target evaluation. To this end, we conducted a transcriptome-wide survey of tissue-specific gene expression and splicing events in the unprecedented collection of 8527 high-quality RNA-seq samples from the GTEx p...

Alternative Titles

Full title

A systematic survey of human tissue-specific gene expression and splicing reveals new opportunities for therapeutic target identification and evaluation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2068831941

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068831941

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/311563