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TGF- induced CXCL13 in CD8+ T cells is associated with tertiary lymphoid structures in cancer

TGF- induced CXCL13 in CD8+ T cells is associated with tertiary lymphoid structures in cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068836775

TGF- induced CXCL13 in CD8+ T cells is associated with tertiary lymphoid structures in cancer

About this item

Full title

TGF- induced CXCL13 in CD8+ T cells is associated with tertiary lymphoid structures in cancer

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2018-04

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Coordinated immune responses against human tumors are frequently characterized by tertiary lymphoid structures (TLS) which predict improved prognosis. The development of TLS is dependent on the chemokine CXCL13, reported to be secreted by dendritic cells and follicular helper T cells only. We report the unexpected finding that CXCL13 is also secret...

Alternative Titles

Full title

TGF- induced CXCL13 in CD8+ T cells is associated with tertiary lymphoid structures in cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2068836775

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068836775

Other Identifiers

DOI

10.1101/303834