X Chromosome Dosage Modulates Multiple Molecular and Cellular Properties of Mouse Pluripotent Stem C...
X Chromosome Dosage Modulates Multiple Molecular and Cellular Properties of Mouse Pluripotent Stem Cells Independently of Global DNA Methylation Levels
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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During early mammalian development, the two X-chromosomes in female cells are active. Dosage compensation between XX female and XY male cells is then achieved by X-chromosome inactivation in female cells. Reprogramming female mouse somatic cells into induced pluripotent stem cells (iPSCs) leads to X-chromosome reactivation. The extent to which incr...
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X Chromosome Dosage Modulates Multiple Molecular and Cellular Properties of Mouse Pluripotent Stem Cells Independently of Global DNA Methylation Levels
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TN_cdi_proquest_journals_2068979499
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068979499
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2692-8205
DOI
10.1101/291450
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https://www.proquest.com/docview/2068979499?pq-origsite=primo&accountid=13902