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Transcriptional deconvolution reveals consistent functional subtypes of pancreatic cancer epithelium...

Transcriptional deconvolution reveals consistent functional subtypes of pancreatic cancer epithelium...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068985554

Transcriptional deconvolution reveals consistent functional subtypes of pancreatic cancer epithelium and stroma

About this item

Full title

Transcriptional deconvolution reveals consistent functional subtypes of pancreatic cancer epithelium and stroma

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2018-03

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Bulk tumor tissues comprise intermixed populations of neoplastic cells and multiple stromal cell lineages. We used laser capture microdissection and RNA sequencing to disentangle the transcriptional programs active in the malignant epithelium and stroma of pancreatic ductal adenocarcinoma (PDA). This led to the development of a new algorithm (ADVOC...

Alternative Titles

Full title

Transcriptional deconvolution reveals consistent functional subtypes of pancreatic cancer epithelium and stroma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2068985554

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068985554

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/288779