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Genome-scale transcriptional regulatory network models of psychiatric and neurodegenerative disorder...

Genome-scale transcriptional regulatory network models of psychiatric and neurodegenerative disorder...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2069685503

Genome-scale transcriptional regulatory network models of psychiatric and neurodegenerative disorders

About this item

Full title

Genome-scale transcriptional regulatory network models of psychiatric and neurodegenerative disorders

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2017-09

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Genetic and genomic studies suggest an important role for transcriptional regulatory changes in brain diseases, but roles for specific transcription factors (TFs) remain poorly understood. We integrated human brain-specific DNase I footprinting and TF-gene co-expression to reconstruct a transcriptional regulatory network (TRN) model for the human b...

Alternative Titles

Full title

Genome-scale transcriptional regulatory network models of psychiatric and neurodegenerative disorders

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2069685503

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2069685503

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/190959