C3G dynamically associates with Nuclear speckles and regulates mRNA splicing
C3G dynamically associates with Nuclear speckles and regulates mRNA splicing
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
C3G (RapGEF1), essential for mammalian embryonic development, is ubiquitously expressed and undergoes regulated nucleo-cytoplasmic exchange. Here we show that C3G localizes to SC35 positive nuclear speckles, and regulates splicing activity. Reversible association of C3G with speckles was seen upon inhibition of transcription and splicing. C3G shows...
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Full title
C3G dynamically associates with Nuclear speckles and regulates mRNA splicing
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TN_cdi_proquest_journals_2069793659
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2069793659
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E-ISSN
2692-8205
DOI
10.1101/159269
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https://www.proquest.com/docview/2069793659?pq-origsite=primo&accountid=13902
