Echinocandin antifungal drugs
Echinocandin antifungal drugs
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Publisher
London: Elsevier Ltd
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Language
English
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Publisher
London: Elsevier Ltd
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Contents
The echinocandins are large lipopeptide molecules that are inhibitors of β-(1,3)-glucan synthesis, an action that damages fungal cell walls. In vitro and in vivo, the echinocandins are rapidly fungicidal against most Candida spp and fungistatic against Aspergillus spp. They are not active at clinically relevant concentrations against Zygomycetes, C...
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Full title
Echinocandin antifungal drugs
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TN_cdi_proquest_journals_2069944896
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2069944896
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(03)14472-8