Specificity Principles in RNA-Guided Targeting
Specificity Principles in RNA-Guided Targeting
About this item
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
RNA-guided nucleases (RGNs) provide sequence-specific gene regulation through base-pairing interactions between a small RNA guide and target RNA or DNA. RGN systems, which include CRISPR-Cas9 and RNA interference (RNAi), hold tremendous promise as programmable tools for engineering and therapeutic purposes. However, pervasive targeting of sequences...
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Full title
Specificity Principles in RNA-Guided Targeting
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TN_cdi_proquest_journals_2070656844
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2070656844
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E-ISSN
2692-8205
DOI
10.1101/055954
How to access this item
https://www.proquest.com/docview/2070656844?pq-origsite=primo&accountid=13902
