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Engrafted parenchymal brain macrophages differ from host microglia in transcriptome, epigenome and r...

Engrafted parenchymal brain macrophages differ from host microglia in transcriptome, epigenome and r...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2070734137

Engrafted parenchymal brain macrophages differ from host microglia in transcriptome, epigenome and response to challenge

About this item

Full title

Engrafted parenchymal brain macrophages differ from host microglia in transcriptome, epigenome and response to challenge

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2018-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Microglia are yolk sac-derived macrophages residing in the parenchyma of brain and spinal cord, where they interact with neurons and other glial cells by constantly probing their surroundings with dynamic extensions. Following different conditioning paradigms and bone marrow (BM) / hematopoietic stem cell (HSC) transplantation, graft-derived cells...

Alternative Titles

Full title

Engrafted parenchymal brain macrophages differ from host microglia in transcriptome, epigenome and response to challenge

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2070734137

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2070734137

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/369942