Purging of deleterious variants due to drift and founder effect in Italian populations with extended...
Purging of deleterious variants due to drift and founder effect in Italian populations with extended autozygosity
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Purging through inbreeding occurs when consanguineous marriages increases the rate at which deleterious alleles are present in a homozygous state. In this study we carried out low-read depth (4-10x) whole-genome sequencing in 568 individuals from three Italian founder populations, and compared it to data from other Italian and European populations...
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Full title
Purging of deleterious variants due to drift and founder effect in Italian populations with extended autozygosity
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TN_cdi_proquest_journals_2070804689
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2070804689
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E-ISSN
2692-8205
DOI
10.1101/022947
How to access this item
https://www.proquest.com/docview/2070804689?pq-origsite=primo&accountid=13902
